Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1880136

N.O=P(O)(OCCO)OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.37
PLA2G2C Q5R387 1/20 0.36
BTN3A1 O00481 1/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MVD P53602 2/20 0.32
LPAR3 Q9UBY5 3/20 0.31
LPAR1 Q92633 2/20 0.31
LPAR2 Q9HBW0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532831 0.97 PPARD (0.39) PPARDPLA2G2CBTN3A1TSHRMAPK1
Hydrochloric Acid SCHEMBL31256693 0.94 PPARD (0.37) PPARDPLA2G2CBTN3A1TSHRMAPK1
SCHEMBL17930259 0.94 PPARD (0.37) PPARDPLA2G2CBTN3A1TSHRMAPK1
SCHEMBL27635097 0.94 PPARD (0.37) PPARDPLA2G2CBTN3A1TSHRMAPK1
Ethylene Glycol SCHEMBL28134638 0.94 PPARD (0.37) PPARDPLA2G2CBTN3A1TSHRMAPK1
SCHEMBL28203342 0.92 PPARD (0.36) PPARDPLA2G2CBTN3A1TSHRMAPK1
SCHEMBL29011435 0.89 PLA2G2C (0.35) PPARDPLA2G2CBTN3A1TSHRMAPK1
SCHEMBL17488889 0.86 BTN3A1 (0.43) PPARDPLA2G2CBTN3A1TSHRMAPK1
SCHEMBL6393988 0.85 PLA2G2C (0.33) PPARDPLA2G2CBTN3A1TSHR
Ammonia Solution, Strong SCHEMBL27549149 0.85 PPARD (0.37) PPARDPLA2G2CBTN3A1MVDLPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6884835-B2 Process for making light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-04-26 US claimed
US-20040162379-A1 Light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY 2004-08-19 US claimed
US-6727311-B2 TIRE TRANSMISSION BELTS, TIRES THE GOODYEAR TIRE & RUBBER COMPANY 2004-04-27 US claimed
US-20030144401-A1 Nanocomposite of elastomer and dispersion therein of intercalated clay prepared in an aqueous medium with functional elastomer GOODYEAR TIRE & RUBBER COMPANY, THE 2003-07-31 US claimed
US-20030004250-A1 Light weight rubber composition containing clay GOODYEAR TIRE & RUBBER COMPANY, THE 2003-01-02 US claimed
EP-0103698-B1 PROCESS FOR THE PRODUCTION OF HOMO- AND CO-POLYMERS OF QUATERNARY AMMONIUM MONOMERS National Starch and Chemical Corporation (US) 1985-12-04 EP claimed
US-4517351-A STORAGE STABLE NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1985-05-14 US claimed
US-4455408-A Process for reacting quaternary ammonium monomers in the presence of anionic polymers NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1984-06-19 US claimed
US-4452957-A SIMULTANEOUS POLYMERIZATION AND DRYING OF A SOLUTION OF MONOMER, FREE-RADICAL CATALYST AND SOLVENT NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1984-06-05 US claimed
EP-0103698-A1 Process for the production of homo- and co-polymers of quaternary ammonium monomers National Starch and Chemical Corporation (US) 1984-03-28 EP claimed
US-7935184-B2 Method of preparing imidazolium surfactants BRIDGESTONE CORPORATION (JP) 2011-05-03 US disclosed
US-7601772-B2 Nano-composite and method thereof BRIDGESTONE CORPORATION 2009-10-13 US disclosed
WO-2007149842-A2 METHOD OF PREPARING IMIDAZOLIUM SURFACTANTS BRIDGESTONE CORPORATION (JP) 2007-12-27 WO disclosed
US-20070293684-A1 Method of preparing imidazolium surfactants BRIDGESTONE CORPORATION 2007-12-20 US disclosed
US-20070161734-A1 Comprising clay and cationic mediator such as imidazolium compound wherein cationic mediator comprises hydrophobic unit and cationic unit; use in preparing products such as tires with improved and well-balanced properties including gas impermeability, cure rates, and superior mechanical characteristics BRIDGESTONE CORPORATION (JP) 2007-07-12 US disclosed
US-20040162379-A1 Light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY 2004-08-19 US disclosed
US-6759464-B2 FUNCTIONALIZED ELASTOMERS WITH INTERCALCATED AND PARTIALLY EXFOLIATED, SWELLABLE CLAY; TIRE TREAD, SIDEWALL AND/OR INNERLINER THE GOODYEAR TIRE & RUBBER COMPANY 2004-07-06 US disclosed
US-6727311-B2 TIRE TRANSMISSION BELTS, TIRES THE GOODYEAR TIRE & RUBBER COMPANY 2004-04-27 US disclosed
US-20030144401-A1 Nanocomposite of elastomer and dispersion therein of intercalated clay prepared in an aqueous medium with functional elastomer GOODYEAR TIRE & RUBBER COMPANY, THE 2003-07-31 US disclosed
US-20030004250-A1 Light weight rubber composition containing clay GOODYEAR TIRE & RUBBER COMPANY, THE 2003-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293684-A1 Method of preparing imidazolium surfactants SMARCC2, SMARCC1, ITPR3 PPARD 4090/4885PLA2G2C 159/4885BTN3A1 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.