SCHEMBL18801418

SCHEMBL18801418

Cc1ccc(N(c2ccccc2)c2ccc(-c3ccccc3-c3ccc(N(c4ccccc4)c4ccc(-c5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.44
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
NTSR1 P30989 1/20 0.42
TDP1 Q9NUW8 3/20 0.42
CYP2C19 P33261 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 2/20 0.40
PTGS2 P35354 1/20 0.40
POLB P06746 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22079686 0.98 HPRT1 (0.45) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL20086814 0.98 TDP1 (0.43) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL22079954 0.98 HPRT1 (0.45) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL20086819 0.98 HPRT1 (0.45) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL13135372 0.94 ALDH1A1 (0.43) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL23972182 0.92 ALDH1A1 (0.48) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL10029846 0.92 ALDH1A1 (0.48) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL19391483 0.92 ALDH1A1 (0.48) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL12249795 0.92 ALDH1A1 (0.48) HPRT1NPC1RAB9ANTSR1TDP1
SCHEMBL17735815 0.92 ALDH1A1 (0.48) HPRT1NPC1RAB9ANTSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3163644-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-05-03 EP disclosed