SCHEMBL188023

SCHEMBL188023

COC(=O)OC1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.53
NAAA Q02083 2/20 0.44
HTT P42858 2/20 0.43
CYP19A1 P11511 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPSR1 Q6W5P4 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873000 1.00 EPHX1 (0.53) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL11591329 1.00 EPHX1 (0.53) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL10598881 1.00 EPHX1 (0.53) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL11589164 1.00 EPHX1 (0.53) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL8582705 1.00 EPHX1 (0.53) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL11593674 1.00 EPHX1 (0.53) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL1081048 0.98 EPHX1 (0.52) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL305953 0.98 EPHX1 (0.50) EPHX1NAAAHTTCYP19A1CA12
SCHEMBL698655 0.93
SCHEMBL10344338 0.93 EPHX1 (0.45) EPHX1NAAAHTTCYP19A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110957533-B Low-temperature electrolyte for lithium ion battery 永州市华米新能源科技有限公司 2025-01-24 CN claimed
CN-115856171-A Method for simultaneously detecting multiple fat-soluble vitamins and multiple steroid hormones 湖南华务星辰医学检验实验室有限公司 2023-03-28 CN claimed
CN-110957533-A Low-temperature electrolyte for lithium ion battery 深圳市东聚能源科技有限公司 2020-04-03 CN claimed
CN-107417641-A Benzothiadiazine analog derivative and preparation method and application 山东大学 2017-12-01 CN claimed
EP-2793887-B1 SULPHONYLAMINOPYRROLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION SANOFI SA (FR) 2015-10-21 EP claimed
US-9150544-B2 Sulphonylaminopyrrolidinone derivatives, their preparation and their therapeutic application SANOFI (FR) 2015-10-06 US claimed
US-20140329801-A1 SULPHONYLAMINOPYRROLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI (FR) 2014-11-06 US claimed
EP-2793887-A1 SULPHONYLAMINOPYRROLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI (FR) 2014-10-29 EP claimed
EP-2189443-B1 TRICYCLIC AMIDE COMPOUND RES FOUND ITSUU LAB (JP) 2013-10-23 EP claimed
WO-2013092756-A1 SULPHONYLAMINOPYRROLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI (FR) 2013-06-27 WO claimed
WO-1995011905-A1 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES SMITHKLINE BEECHAM PLC (GB) 1995-05-04 WO claimed
EP-0639193-A1 ESTERS OF ANTIBACTERIAL CONDENSED CARBAPENEME DERIVATIVES GLAXO S.p.A. (IT) 1995-02-22 EP claimed
EP-0603001-A1 Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease SANKYO COMPANY LIMITED (JP) 1994-06-22 EP claimed
EP-0495953-B1 10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo[7.2.0.0(3,8)]undec-2-ene-2-carboxylic acid esters and a process for preparing thereof GLAXO SPA (IT) 1994-06-08 EP claimed
EP-0557167-A1 Preparation of fluorinated functional compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-25 EP claimed
WO-1992015588-A1 ESTERS OF ANTIBACTERIAL CONDENSED CARBAPENEME DERIVATIVES GLAXO S.P.A. (IT) 1992-09-17 WO claimed
EP-0502465-A1 Esters of antibacterial condensed carbapenemederivatives GLAXO S.p.A. (IT) 1992-09-09 EP claimed
EP-0495953-A1 10-(1-Hydoxyethyl)-11-oxo-1-azatricyclo(7.2.0.0(3,8)undec-2-ene-2-carboxylic acid esters and a process for preparing thereof. GLAXO SPA (IT) 1992-07-29 EP claimed
WO-1992003437-A1 10(1-HYDROXYETHYL)-11-OXO-1-AZATRICYCLO[7.2.0.0.3.8]UNDEC-2-ENE-2-CARBOXYLIC ACID ESTERS AND A PROCESS FOR PREPARING THEREOF GLAXO S.P.A. (IT) 1992-03-05 WO claimed
EP-0128029-B1 CEPHALOSPORIN ESTER DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140329801-A1 SULPHONYLAMINOPYRROLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION F9, TFPI, SERPINC1 EPHX1 1946/4885NAAA 525/4885HTT 2347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.