Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315235 | 0.80 | BCHE (0.35) | ESR1MEN1KMT2ABRD4TNF | |
| SCHEMBL30261030 | 0.78 | BRD4 (0.45) | MEN1POLBMAPK1KMT2ABRD4 | |
| SCHEMBL7835424 | 0.78 | BRD4 (0.45) | MEN1POLBMAPK1KMT2ABRD4 | |
| SCHEMBL20354829 | 0.77 | AHR (0.47) | MEN1POLBMAPK1KMT2ABRD4 | |
| SCHEMBL2305754 | 0.77 | BRD4 (0.41) | MEN1POLBMAPK1KMT2ABRD4 | |
| SCHEMBL1162240 | 0.75 | KDM4E (0.42) | CA1CA12CA7CA9POLB | |
| SCHEMBL28878115 | 0.75 | KEAP1 (0.53) | MEN1POLBMAPK1KMT2AMAPT | |
| SCHEMBL15550121 | 0.74 | KEAP1 (0.40) | MEN1POLBMAPK1KMT2ABRD4 | |
| SCHEMBL8055277 | 0.74 | TNF (0.39) | ESR1ESR2BRD4TNFRIPK1 | |
| SCHEMBL9315426 | 0.73 | MCL1 (0.42) | MEN1POLBMAPK1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103517703-B | Stain and application thereof | 天野酶制品株式会社 | 2016-11-09 | — | — | CN | claimed |
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | claimed |
| CN-103998016-B | Employ the dyeing of the keratin fiber of indole analog | AMANO ENZYME INC. (JP) | 2015-09-16 | — | — | CN | claimed |
| CN-103408554-B | Hypertensive activity reducing pyrrole coumarins compound and preparation method thereof | UNIV XI AN JIAOTONG | 2015-07-08 | — | — | CN | claimed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | claimed |
| CN-103408554-A | Hypertensive activity reducing pyrrole coumarins compound and preparation method thereof | UNIV XI AN JIAOTONG | 2013-11-27 | — | — | CN | claimed |
| EP-0597022-B2 | PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES | OREAL (FR) | 1999-11-17 | — | — | EP | claimed |
| US-5874091-A | PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. | L'OREAL (FR) | 1999-02-23 | — | — | US | claimed |
| EP-0587837-B1 | Cosmetic composition containing melanistic pigments in association with certain tocopherols, and method for protecting the skin, the hair, the mucous membranes and cosmetic compositions | OREAL (FR) | 1998-06-03 | — | — | EP | claimed |
| EP-0544874-B1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | OREAL (FR) | 1998-04-08 | — | — | EP | claimed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | claimed |
| EP-0518773-A1 | Cosmetic composition containing a blend of metallic oxids nanopigments and melanic pigments | L'OREAL (FR) | 1992-12-16 | — | — | EP | claimed |
| EP-0504347-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS. | OREAL (FR) | 1992-09-23 | — | — | EP | claimed |
| EP-0500446-A1 | Skin-tanning composition containing indole derivatives and dihydroxyacetone | L'OREAL (FR) | 1992-08-26 | — | — | EP | claimed |
| WO-1992005761-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS | L'OREAL (FR) | 1992-04-16 | — | — | WO | claimed |
| EP-0467767-A1 | Product based on flaky particles containing melanine pigment and process for their preparation | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |
| EP-0446132-A1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| EP-0379409-A1 | Products based on polymer particles containing melanine pigments, process for their preparation, and their use, particularly cosmetically | L'OREAL (FR) | 1990-07-25 | — | — | EP | claimed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | claimed |