Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22369614 | 0.85 | ELANE (0.86) | ELANEPRTN3 | |
| SCHEMBL4639551 | 0.84 | ELANE (1.00) | ELANE | |
| SCHEMBL11336605 | 0.82 | ELANE (0.75) | ELANEPRTN3 | |
| SCHEMBL23759975 | 0.82 | ELANE (0.75) | ELANEPRTN3 | |
| SCHEMBL386689 | 0.82 | ELANE (0.75) | ELANEPRTN3 | |
| SCHEMBL10483695 | 0.80 | ELANE (1.00) | ELANE | |
| SCHEMBL197454 | 0.80 | ELANE (0.83) | ELANE | |
| SCHEMBL10483745 | 0.79 | ELANE (1.00) | ELANEPRTN3 | |
| SCHEMBL13998362 | 0.79 | ELANE (0.76) | ELANEPRTN3 | |
| SCHEMBL8403640 | 0.79 | ELANE (0.81) | ELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60237049-A | — | — | None | — | — | JP | disclosed |
| US-7935674-B2 | Indole derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-05-03 | — | — | US | disclosed |
| US-20090258921-A1 | INDOLE DERIVATIVES | NOMURA SUMIHIRO | 2009-10-15 | — | — | US | disclosed |
| US-20080119422-A1 | Indole Derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1863798-A1 | INDOLE DERIVATIVES | Mitsubishi Tanabe Pharma Corporation (JP) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006080577-A1 | INDOLE DERIVATIVES | TANABE SEIYAKU CO., LTD. (JP) | 2006-08-03 | — | — | WO | disclosed |
| JP-S60237049-A | P-HYDROXYBENZOIC ACID COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1985-11-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258921-A1 | INDOLE DERIVATIVES | IDO1, TPH1, NAT1 | ELANE 3926/4885PRTN3 2004/4885 |
| US-20080119422-A1 | Indole Derivatives | IDO1, TPH1, NAT1 | ELANE 3926/4885PRTN3 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.