SCHEMBL18808192

SCHEMBL18808192

C=CC(=O)Oc1ccc(-c2ccc(-c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.54
TGM2 P21980 1/20 0.51
LMNA P02545 1/20 0.51
ESR2 Q92731 1/20 0.50
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
BACE1 P56817 1/20 0.46
TP53 P04637 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18468213 1.00 THRB (0.54) THRBTGM2LMNAESR2HDAC8
SCHEMBL1061204 0.94 THRB (0.59) THRBTGM2LMNASMN1; SMN2CES2
SCHEMBL21470016 0.90 KMT2A (0.56) THRBLMNANPC1RAB9ASMN1; SMN2
SCHEMBL22148977 0.90 THRB (0.50) THRBTGM2LMNAESR2HDAC8
SCHEMBL20105062 0.90 KMT2A (0.56) THRBLMNANPC1RAB9ASMN1; SMN2
SCHEMBL13859677 0.90 KMT2A (0.56) THRBLMNANPC1RAB9ASMN1; SMN2
SCHEMBL802752 0.90 THRB (0.58) THRBTGM2LMNANPC1RAB9A
SCHEMBL15695636 0.90 THRB (0.58) THRBTGM2LMNANPC1RAB9A
Acrylic Acid SCHEMBL28864006 0.89 THRB (0.54) THRBTGM2LMNASMN1; SMN2CES2
SCHEMBL10015746 0.87 KMT2A (0.61) THRBLMNAHDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-4249570-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2023-09-27 EP disclosed
EP-3551723-B1 ADDITIVES FOR LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2023-09-20 EP disclosed
EP-3870671-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-08-09 EP disclosed
EP-4219656-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS Merck Patent GmbH (DE) 2023-08-02 EP disclosed
EP-3839008-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-07-26 EP disclosed
EP-4209567-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
EP-4209568-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
EP-4209566-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2023-07-12 EP disclosed
EP-3353261-B1 METHOD OF CONTROLLING THE PRETILT ANGLE IN POLYMER STABILISED LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2020-05-27 EP disclosed
EP-3323872-B1 COMPOUNDS FOR HOMOTROPIC ALIGNMENT OF LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2020-04-15 EP disclosed
EP-3628721-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-04-01 EP disclosed
EP-3604481-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-02-05 EP disclosed
EP-3121247-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2019-10-02 EP disclosed
EP-3387089-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2019-10-02 EP disclosed
EP-3246374-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2019-08-14 EP disclosed
EP-3298105-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2019-03-20 EP disclosed
EP-3284803-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2019-01-23 EP disclosed
EP-3162875-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS Merck Patent GmbH (DE) 2017-05-03 EP disclosed