Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.62 |
| ▸ | AVPR1A | P37288 | 14/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18808968 | 0.91 | AVPR2 (0.74) | AVPR2AVPR1APTGS2 | |
| SCHEMBL18808850 | 0.88 | AVPR2 (0.64) | AVPR2AVPR1AAMY1ASLC5A2 | |
| SCHEMBL2439956 | 0.85 | AVPR2 (0.84) | AVPR2AVPR1A | |
| SCHEMBL18808828 | 0.83 | AVPR2 (0.52) | AVPR2AVPR1AAMY1A | |
| SCHEMBL18808721 | 0.78 | AVPR2 (0.46) | AVPR2AVPR1A | |
| SCHEMBL18808889 | 0.77 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL24010779 | 0.77 | AVPR2 (0.50) | AVPR2AVPR1A | |
| SCHEMBL19568127 | 0.77 | AVPR2 (0.52) | AVPR2AVPR1A | |
| SCHEMBL18808707 | 0.77 | AVPR2 (0.74) | AVPR2AVPR1A | |
| SCHEMBL6926677 | 0.77 | AVPR2 (1.00) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539326-B1 | BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF | BAYER IP GMBH (DE) | 2017-05-03 | — | — | EP | disclosed |