Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15964704 | 0.80 | OPRK1 (0.47) | ALDH1A1 | |
| SCHEMBL12632993 | 0.79 | HRH3 (0.65) | EPHX2HRH3KMT2AMEN1 | |
| SCHEMBL17321255 | 0.78 | GRM5 (0.46) | EPHX2 | |
| SCHEMBL23066789 | 0.77 | OPRK1 (0.47) | ALDH1A1 | |
| SCHEMBL29770585 | 0.77 | OPRK1 (0.47) | ALDH1A1 | |
| SCHEMBL18808825 | 0.77 | EPHX2 (0.56) | EPHX2 | |
| SCHEMBL12355370 | 0.76 | HRH3 (0.58) | EPHX2HRH3KMT2AMEN1TRPC6 | |
| SCHEMBL18808967 | 0.75 | EPHX2 (0.54) | EPHX2CFTR | |
| SCHEMBL1807784 | 0.75 | ACACB (0.49) | EPHX2HRH3KMT2AALDH1A1HTT | |
| SCHEMBL15611977 | 0.75 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675274-B1 | SORAFENIB DERIVATIVES AS sEH INHIBITORS | UNIV CALIFORNIA (US) | 2017-05-03 | — | — | EP | disclosed |