Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133789 | 0.94 | CYP3A4 (0.36) | — | |
| SCHEMBL18809159 | 0.88 | CNR1 (0.38) | CNR1CNR2BCHE | |
| SCHEMBL19401361 | 0.87 | CYP3A4 (0.38) | — | |
| SCHEMBL19385683 | 0.87 | CYP3A4 (0.40) | — | |
| SCHEMBL18809185 | 0.86 | CYP3A4 (0.36) | — | |
| SCHEMBL16133761 | 0.83 | CYP3A4 (0.39) | CNR1CNR2 | |
| SCHEMBL16133790 | 0.82 | CYP3A4 (0.39) | — | |
| SCHEMBL19401414 | 0.78 | CYP3A4 (0.41) | — | |
| SCHEMBL17464394 | 0.78 | CNR2 (0.37) | CNR2 | |
| SCHEMBL19401330 | 0.77 | CYP2C8 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970174-B1 | FUSED FURANS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |