Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19401361 | 0.89 | CYP3A4 (0.38) | CYP3A4CYP2C8 | |
| SCHEMBL19385683 | 0.89 | CYP3A4 (0.40) | CYP3A4CYP2C8 | |
| SCHEMBL16133789 | 0.89 | CYP3A4 (0.36) | CYP3A4CYP2C8 | |
| SCHEMBL18809302 | 0.87 | ALDH1A1 (0.38) | CYP3A4CYP2C8 | |
| SCHEMBL18809153 | 0.86 | CNR1 (0.37) | — | |
| SCHEMBL18809160 | 0.86 | CYP3A4 (0.38) | CYP3A4CYP2C8 | |
| SCHEMBL16133761 | 0.85 | CYP3A4 (0.39) | CYP3A4CYP2C8 | |
| SCHEMBL19401414 | 0.80 | CYP3A4 (0.41) | CYP3A4CYP2C8 | |
| SCHEMBL17464394 | 0.80 | CNR2 (0.37) | CYP3A4CYP2C8 | |
| SCHEMBL19262507 | 0.79 | CYP3A4 (0.37) | CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738653-B2 | Fused furans for the treatment of hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-08-22 | — | — | US | disclosed |
| EP-2970174-B1 | FUSED FURANS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |