Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PRNP | P04156 | 1/20 | 0.56 |
| ▸ | ANO1 | Q5XXA6 | 14/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18038582 | 0.85 | MEN1 (0.52) | MEN1KMT2APRNP | |
| SCHEMBL3538490 | 0.83 | ANO1 (0.55) | MEN1KMT2APRNPANO1KDM4E | |
| SCHEMBL1918771 | 0.80 | ANO1 (0.45) | MEN1KMT2APRNPANO1ACHE | |
| SCHEMBL3541223 | 0.80 | ANO1 (0.48) | MEN1KMT2APRNPANO1KDM4E | |
| SCHEMBL1918164 | 0.80 | RAB9A (0.60) | MEN1KMT2AANO1KDM4EALDH1A1 | |
| SCHEMBL27996553 | 0.80 | KDM4E (0.51) | MEN1KMT2AANO1ACHEBACE1 | |
| SCHEMBL14710224 | 0.78 | ANO1 (0.56) | MEN1KMT2AANO1KDM4EALDH1A1 | |
| SCHEMBL14709425 | 0.78 | ANO1 (0.47) | MEN1KMT2AANO1KDM4EALDH1A1 | |
| SCHEMBL2401183 | 0.77 | ANO1 (0.45) | MEN1KMT2APRNPANO1KDM4E | |
| SCHEMBL2402437 | 0.76 | ANO1 (0.46) | ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970174-B1 | FUSED FURANS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |