Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 8/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26240417 | 0.88 | KDM4E (0.58) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL31419639 | 0.80 | GAA (0.51) | ALDH1A1MAPTHPGDHTTGAA | |
| SCHEMBL30848463 | 0.80 | HPGD (0.60) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL24268174 | 0.79 | KDM4E (0.59) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL26240424 | 0.77 | GRM5 (0.52) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL30848467 | 0.76 | CNR2 (0.89) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL31191005 | 0.75 | TSHR (1.00) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL15121240 | 0.75 | TSHR (1.00) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL10928771 | 0.75 | KDM4E (0.72) | ALDH1A1MAPTHPGDKDM4ETSHR | |
| SCHEMBL3709144 | 0.74 | KDM4E (0.70) | ALDH1A1MAPTHPGDKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970174-B1 | FUSED FURANS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |