Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 11/20 | 0.58 |
| ▸ | FAAH | O00519 | 4/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18809491 | 0.80 | ALDH1A1 (0.60) | HPGDKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL30848467 | 0.80 | CNR2 (0.89) | HPGDKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL24268174 | 0.79 | KDM4E (0.59) | HPGDKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL30848451 | 0.79 | HPGD (0.47) | HPGDHTTP2RX7NPC1RAB9A | |
| SCHEMBL7446480 | 0.78 | P2RX7 (0.47) | HPGDALDH1A1MAPTHTTATM | |
| SCHEMBL397839 | 0.76 | HPGD (0.51) | HPGDHTTP2RX7NPC1RAB9A | |
| SCHEMBL10928771 | 0.75 | KDM4E (0.72) | HPGDKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL31191005 | 0.75 | TSHR (1.00) | HPGDKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL27847002 | 0.75 | HPGD (0.47) | HPGDMAPTHTTP2RX7NPC1 | |
| SCHEMBL15121240 | 0.75 | TSHR (1.00) | HPGDKDM4EALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |