SCHEMBL18810073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1267742	0.85	L3MBTL1 (0.57)	L3MBTL1ALDH1A1POLBKDM4EMAPT
	SCHEMBL29417154	0.85	L3MBTL1 (0.57)	L3MBTL1ALDH1A1POLBKDM4EMAPT
	SCHEMBL20489778	0.83	L3MBTL1 (0.50)	L3MBTL1ALDH1A1POLBKDM4ESCN9A
	SCHEMBL29417209	0.83	L3MBTL1 (0.50)	L3MBTL1ALDH1A1POLBKDM4ESCN9A
	SCHEMBL28414002	0.81	APP (0.60)	L3MBTL1ALDH1A1POLBKDM4EAPP
	SCHEMBL29417178	0.80	KDM4E (0.50)	L3MBTL1ALDH1A1POLBKDM4EAPP
	SCHEMBL9446790	0.80	KDM4E (0.50)	L3MBTL1ALDH1A1POLBKDM4EAPP
	SCHEMBL22190226	0.78	APP (0.47)	L3MBTL1ALDH1A1POLBKDM4EAPP
	SCHEMBL18810348	0.78	KDM4E (0.49)	L3MBTL1ALDH1A1POLBKDM4EAPP
	SCHEMBL20489915	0.78	KDM4E (0.49)	L3MBTL1ALDH1A1POLBKDM4EAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.