SCHEMBL18812934

SCHEMBL18812934

CCCC1(CCC)c2ccccc2-c2ccc(C(=O)C(=NO)c3ccccc3C)cc21

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 1/20 0.36
▸ PDK2 Q15119 16/20 0.36
▸ KMT2A Q03164 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HTR7 P34969 1/20 0.32
▸ HTR2B P41595 1/20 0.32
▸ PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18838856 1.00 APEX1 (0.36) APEX1PDK2KMT2ASMN1; SMN2HTR7
SCHEMBL29368666 1.00 APEX1 (0.36) APEX1PDK2KMT2ASMN1; SMN2HTR7
SCHEMBL18812932 1.00 APEX1 (0.36) APEX1PDK2KMT2ASMN1; SMN2HTR7
SCHEMBL18926239 0.92 PDK2 (0.38) PDK2
SCHEMBL18838804 0.88 PDK2 (0.38) APEX1PDK2
SCHEMBL18123006 0.87 PDK2 (0.33) APEX1PDK2KMT2ASMN1; SMN2HTR7
SCHEMBL26443682 0.87 PDK2 (0.33) APEX1PDK2KMT2ASMN1; SMN2HTR7
SCHEMBL29420682 0.86 APEX1 (0.43) APEX1PDK2PGR
SCHEMBL18812920 0.86 APEX1 (0.43) APEX1PDK2PGR
SCHEMBL18812921 0.86 APEX1 (0.43) APEX1PDK2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106371287-B Colored photosensitive composition 东京应化工业株式会社 2022-02-11 — — CN disclosed
CN-106970503-B Photosensitive composition 东京应化工业株式会社 2022-02-01 — — CN disclosed
CN-106019841-B Photosensitive resin composition, pattern forming method, cured film, insulating film, color filter, and display device 东京应化工业株式会社 2021-03-26 — — CN disclosed
CN-106537254-B Photosensitive composition and compound 东京应化工业株式会社 2021-01-08 — — CN disclosed
EP-3165965-B1 PHOTOSENSITIVE COMPOSITION AND COMPOUND TOKYO OHKA KOGYO CO LTD (JP) 2018-10-10 — — EP disclosed
US-20170160636-A1 PHOTOSENSITIVE COMPOSITION AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-08 — — US disclosed
EP-3165965-A1 PHOTOSENSITIVE COMPOSITION AND COMPOUND Tokyo Ohka Kogyo Co., Ltd. (JP) 2017-05-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170160636-A1 PHOTOSENSITIVE COMPOSITION AND COMPOUND C1R, CRY1, C1S APEX1 871/4885PDK2 2998/4885KMT2A 371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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