Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18814521 | 1.00 | EPHX1 (0.50) | EPHX1ALDH1A1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL18804825 | 0.90 | KMT2A (0.54) | EPHX1ALDH1A1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL15262638 | 0.90 | EPHX1 (0.58) | EPHX1ALDH1A1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL2625568 | 0.90 | EPHX1 (0.58) | EPHX1ALDH1A1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL103477 | 0.85 | — | — | |
| SCHEMBL18880078 | 0.85 | SMYD3 (0.47) | EPHX1L3MBTL1ATMEPHX2MAPK8 | |
| SCHEMBL2625559 | 0.84 | EPHX1 (0.61) | EPHX1ALDH1A1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL2625555 | 0.84 | EPHX1 (0.67) | EPHX1ALDH1A1SMN1; SMN2ATMEPHX2 | |
| SCHEMBL23573335 | 0.82 | ALDH1A1 (0.56) | EPHX1ALDH1A1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL14654896 | 0.82 | EPHX1 (0.66) | EPHX1ALDH1A1SMN1; SMN2L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119580-A1 | POLYURETHANE/UREA MATERIALS | FOLDAX, INC. | 2022-04-21 | — | — | US | disclosed |
| US-10266657-B2 | Polyurethane/urea compositions | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2019-04-23 | — | — | US | disclosed |
| US-20170119923-A1 | POLYURETHANE/UREA COMPOSITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION | 2017-05-04 | — | — | US | disclosed |