Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094448 | 0.83 | CYP1A2 (0.57) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL271506 | 0.79 | CYP1A2 (0.59) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL271505 | 0.79 | CYP1A2 (0.53) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL24593163 | 0.79 | CYP1A2 (0.53) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL30618060 | 0.78 | HPGD (0.56) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL29105728 | 0.78 | HPGD (0.56) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL8569257 | 0.75 | CYP1A2 (0.53) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL9620162 | 0.75 | CYP1A2 (0.48) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL455964 | 0.75 | CYP1A2 (0.48) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL28028241 | 0.75 | CYP1A2 (0.48) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | FLI1, ABL1, PFAS | CYP1A2 350/4885PDGFRB 570/4885PDGFRA 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.