Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 6/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815626 | 0.88 | PRCP (0.46) | CYP3A4CYP2C9CYP1A2CYP2D6PRCP | |
| SCHEMBL18815629 | 0.88 | PRCP (0.46) | CYP3A4CYP2C9CYP1A2CYP2D6PRCP | |
| SCHEMBL12066749 | 0.83 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP1A2CYP2D6PRCP | |
| SCHEMBL8885712 | 0.72 | RIPK1 (0.36) | PRCPHCRTR1HCRTR2HPGDSRIPK1 | |
| SCHEMBL4216573 | 0.69 | RIPK1 (0.39) | HCRTR1HCRTR2RIPK1 | |
| SCHEMBL4216577 | 0.69 | RIPK1 (0.39) | HCRTR1HCRTR2RIPK1 | |
| SCHEMBL18815579 | 0.69 | CYP3A4 (0.64) | CYP3A4CYP2C9CYP1A2CYP2D6PRCP | |
| SCHEMBL18815577 | 0.69 | CYP3A4 (0.64) | CYP3A4CYP2C9CYP1A2CYP2D6PRCP | |
| SCHEMBL17069044 | 0.69 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP1A2CYP2D6PRCP | |
| SCHEMBL24993318 | 0.68 | RIPK1 (0.47) | PRCPOPRK1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-05-11 | — | — | US | disclosed |
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | BET1, PRR12, PREP | CYP3A4 3355/4885CYP2C9 4010/4885CYP1A2 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.