Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 9/20 | 0.39 |
| ▸ | BRD2 | P25440 | 5/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889253 | 0.87 | BRD4 (0.39) | MEN1KMT2APIK3CDBRD4BRD2 | |
| SCHEMBL1881999 | 0.79 | MEN1 (0.46) | MEN1KMT2APIK3CDATMDRD4 | |
| SCHEMBL1883185 | 0.78 | ACACB (0.44) | PIK3CDBRD4RXFP1CTSA | |
| SCHEMBL1884046 | 0.77 | ERN1 (0.49) | BRD4BRD2CREBBPNPC1POLB | |
| SCHEMBL1878147 | 0.76 | PIK3CD (0.39) | PIK3CDBRD4BRD2CREBBPPOLB | |
| SCHEMBL1887862 | 0.75 | MEN1 (0.48) | MEN1KMT2APIK3CDATMDRD4 | |
| SCHEMBL1887556 | 0.75 | PIK3CD (0.53) | MEN1KMT2APIK3CDATMDRD4 | |
| SCHEMBL1879223 | 0.74 | MEN1 (0.47) | MEN1KMT2APIK3CDNPC1POLB | |
| SCHEMBL1886286 | 0.73 | PIK3CD (0.54) | MEN1KMT2APIK3CDRAB9AATM | |
| SCHEMBL1883935 | 0.72 | PIK3CD (0.60) | MEN1KMT2APIK3CDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399483-B2 | Quinoxaline and quinoline derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2013-03-19 | — | — | US | disclosed |
| US-20110105508-A1 | QUINOXALINE AND QUINOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA, S.A. (BE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105508-A1 | QUINOXALINE AND QUINOLINE DERIVATIVES AS KINASE INHIBITORS | PDXK, PDPK1, PIKFYVE | MEN1 1813/4885KMT2A 1617/4885PIK3CD 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.