Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819838 | 0.92 | POLB (0.36) | POLBPTGS2PDE10ATRPM8ACSS2 | |
| SCHEMBL25106818 | 0.90 | POLB (0.43) | POLBPDE10ADDR1GRIN1GRIN2B | |
| SCHEMBL18819868 | 0.90 | POLB (0.43) | POLBPDE10ADDR1GRIN1GRIN2B | |
| SCHEMBL25106704 | 0.89 | POLB (0.42) | POLBPDE10ATRPM8DDR1LMNA | |
| SCHEMBL25106702 | 0.89 | POLB (0.41) | POLBPTGS2LMNAHTTALDH1A1 | |
| SCHEMBL25106687 | 0.88 | POLB (0.41) | POLBDDR1HTTKMT2AKDM4E | |
| SCHEMBL25106694 | 0.88 | POLB (0.41) | POLBPDE10ADDR1GRIN1GRIN2B | |
| SCHEMBL25106936 | 0.88 | POLB (0.41) | POLBDDR1LMNAHTTPKM | |
| SCHEMBL25106815 | 0.87 | POLB (0.40) | POLBPDE10ADDR1KMT2AGRIN1 | |
| SCHEMBL18819840 | 0.87 | POLB (0.41) | POLBPTGS2PDE10APTGS1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204499-A1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-06-30 | — | — | US | disclosed |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204499-A1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BCHE, C1R, C1S | POLB 3145/4885PTGS2 1742/4885PDE10A 956/4885 |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | POLB 3595/4885PTGS2 2306/4885PDE10A 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.