SCHEMBL1882012

SCHEMBL1882012

CO[Si](CCCCC(C(=O)O)=C(CCC[Si](OC)(OC)OC)CCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.34
FNTB P49356 2/20 0.34
THRB P10828 1/20 0.34
PGGT1B P53609 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108253 0.87 FNTA (0.35) FNTAFNTBTHRBPGGT1B
SCHEMBL108251 0.87 FNTA (0.35) FNTAFNTBTHRBPGGT1B
SCHEMBL437746 0.87 FNTA (0.35) FNTAFNTBTHRBPGGT1B
SCHEMBL1900885 0.85 FNTA (0.34) FNTAFNTBTHRBPGGT1B
SCHEMBL1903505 0.85 FNTA (0.34) FNTAFNTBTHRBPGGT1B
SCHEMBL15106766 0.84 FNTA (0.37) FNTAFNTB
SCHEMBL7795232 0.78 ALDH1A1 (0.31)
SCHEMBL7795240 0.78 ALDH1A1 (0.31)
SCHEMBL1972438 0.77 ALDH1A1 (0.50)
SCHEMBL1900446 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7934830-B2 High water content silicone hydrogels BAUSCH & LOMB INCORPORATED (US) 2011-05-03 US claimed
US-7934830-B2 High water content silicone hydrogels BAUSCH & LOMB INCORPORATED (US) 2011-05-03 US disclosed