⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820725 | 0.88 | — | — | |
| SCHEMBL18820335 | 0.86 | — | — | |
| SCHEMBL21452682 | 0.65 | MGLL (0.32) | — | |
| SCHEMBL18806108 | 0.61 | CYP11B1 (0.43) | — | |
| SCHEMBL1557616 | 0.60 | NEK2 (0.43) | — | |
| SCHEMBL21201884 | 0.59 | CYP11B1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL21434095 | 0.58 | NEK2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL22576417 | 0.58 | NEK2 (0.42) | — | |
| SCHEMBL24004287 | 0.57 | CYP11B1 (0.41) | — | |
| SCHEMBL12658986 | 0.56 | NEK2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828373-B2 | 2-amino-pyrido[2,3-D]pyrimidin-7(8H)-one derivatives as CDK inhibitors and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-11-28 | — | — | US | disclosed |
| US-20170121323-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |