Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18822013 | 0.87 | F11 (0.59) | F11KLK1 | |
| SCHEMBL18822005 | 0.85 | F11 (0.51) | F11KLK1 | |
| SCHEMBL615348 | 0.85 | F11 (0.51) | F11KLK1 | |
| SCHEMBL615347 | 0.85 | F11 (0.51) | F11KLK1 | |
| SCHEMBL22294405 | 0.84 | F11 (0.51) | F11KLK1 | |
| SCHEMBL18822354 | 0.83 | F11 (0.63) | F11KLK1 | |
| SCHEMBL18822372 | 0.82 | F11 (0.55) | F11KLK1 | |
| SCHEMBL18822531 | 0.80 | F9 (0.42) | F11KLK1 | |
| SCHEMBL16408921 | 0.80 | F11 (0.53) | F11 | |
| SCHEMBL16408920 | 0.80 | F11 (0.53) | F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017074833-A1 | MACROCYCLIC SPIROCARBAMATE DERIVATIVES AS FACTOR XIA INHIBITORS, PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME CORP. (US) | 2017-05-04 | — | — | WO | disclosed |