⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283954 | 1.00 | — | — | |
| SCHEMBL284682 | 0.98 | — | — | |
| SCHEMBL284622 | 0.93 | — | — | |
| SCHEMBL12891800 | 0.83 | — | — | |
| SCHEMBL20880492 | 0.83 | CA1 (0.33) | — | |
| SCHEMBL10901618 | 0.80 | SLC6A4 (0.35) | — | |
| SCHEMBL7517584 | 0.79 | CYP1A2 (0.30) | — | |
| SCHEMBL24925663 | 0.78 | TDP1 (0.40) | — | |
| SCHEMBL20763613 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL10145978 | 0.77 | SLC6A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017075522-A2 | GLP-2 POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017075505-A2 | NOVEL POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY, AND METHODS OF PREPARING AND USING SAME | TUFTS UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |