Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 14/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345436 | 0.92 | STAT3 (0.51) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345498 | 0.88 | STAT3 (0.56) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18731231 | 0.88 | STAT3 (0.52) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345513 | 0.88 | STAT3 (0.59) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18730823 | 0.88 | STAT3 (0.56) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345568 | 0.88 | STAT3 (0.55) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345431 | 0.88 | STAT3 (0.47) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345471 | 0.87 | STAT3 (0.52) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345495 | 0.87 | STAT3 (0.49) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL21250130 | 0.87 | STAT3 (0.46) | STAT3ALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121299-A1 | NOVEL ANTICANCER AGENT | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121299-A1 | NOVEL ANTICANCER AGENT | NTPCR, TP53, NME1 | STAT3 1231/4885ALDH1A1 187/4885MAPT 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.