Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345436 | 0.92 | STAT3 (0.51) | STAT3ALDH1A1POLBMEN1MAPT | |
| SCHEMBL18731163 | 0.92 | STAT3 (0.38) | STAT3ALDH1A1ITGB3ITGA2BPTPRC | |
| SCHEMBL21250136 | 0.87 | STAT3 (0.48) | STAT3ALDH1A1PTPRCPOLBMEN1 | |
| SCHEMBL18807136 | 0.87 | STAT3 (0.44) | STAT3ALDH1A1GRIN1GRIN2AGRIN2B | |
| SCHEMBL18731231 | 0.87 | STAT3 (0.52) | STAT3ALDH1A1POLBMEN1MAPT | |
| SCHEMBL18822677 | 0.87 | STAT3 (0.52) | STAT3ALDH1A1POLBMEN1MAPT | |
| SCHEMBL18807133 | 0.85 | STAT3 (0.48) | STAT3ALDH1A1L3MBTL1CASP6 | |
| SCHEMBL18807134 | 0.85 | STAT3 (0.48) | STAT3ALDH1A1L3MBTL1CASP6 | |
| SCHEMBL17345448 | 0.85 | STAT3 (0.50) | STAT3ALDH1A1POLBMEN1MAPT | |
| SCHEMBL18731151 | 0.84 | STAT3 (0.53) | STAT3ALDH1A1PTPRCPTPN13MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377730-B2 | Anticancer agent | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377730-B2 | Anticancer agent | TP53, NTPCR, NQO1 | STAT3 1303/4885ALDH1A1 160/4885ITGB3 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.