Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18826529 | 0.77 | MAPT (0.54) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11329226 | 0.73 | MAPT (1.00) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11329248 | 0.73 | MAPT (1.00) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL16556 | 0.73 | MAPT (1.00) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11329238 | 0.73 | MAPT (1.00) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11318226 | 0.73 | MAPT (1.00) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL205992 | 0.73 | MAPT (1.00) | MAPTRAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL9485438 | 0.73 | CYP3A4 (1.00) | MAPTMEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL9649030 | 0.73 | CYP3A4 (1.00) | MAPTMEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL9485453 | 0.73 | CYP3A4 (1.00) | MAPTMEN1KMT2ACYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644071-B1 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2017-05-09 | — | — | US | disclosed |