Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16837891 | 1.00 | LMNA (0.37) | LMNANPSR1CXCR5 | |
| SCHEMBL11375499 | 0.80 | NPSR1 (0.44) | LMNANPSR1 | |
| SCHEMBL21536751 | 0.79 | LMNA (0.36) | LMNANPSR1 | |
| SCHEMBL28176535 | 0.76 | NPSR1 (0.36) | NPSR1 | |
| SCHEMBL16837892 | 0.76 | NPSR1 (0.36) | LMNANPSR1 | |
| SCHEMBL20068373 | 0.75 | LMNA (0.41) | LMNANPSR1 | |
| SCHEMBL9009602 | 0.73 | LMNA (0.42) | LMNANPSR1 | |
| SCHEMBL16104372 | 0.72 | NPSR1 (0.41) | LMNANPSR1 | |
| SCHEMBL15537624 | 0.71 | MEN1 (0.33) | LMNANPSR1 | |
| SCHEMBL5515153 | 0.70 | NPSR1 (0.40) | LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9642889-B2 | Macrocyclic inhibitors of Flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2017-05-09 | — | — | US | disclosed |