Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.62 |
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16065340 | 1.00 | CTSC (0.62) | CTSCCTSKGPR119 | |
| SCHEMBL16065009 | 0.90 | CTSC (0.60) | CTSCCTSK | |
| SCHEMBL18828619 | 0.90 | CTSC (0.60) | CTSCCTSK | |
| SCHEMBL14822119 | 0.87 | CTSC (0.58) | CTSCCTSKGPR119 | |
| SCHEMBL15081644 | 0.87 | CTSC (0.58) | CTSCCTSKGPR119 | |
| SCHEMBL16078802 | 0.87 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL18828646 | 0.86 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL16065145 | 0.86 | CTSC (0.58) | CTSCCTSK | |
| SCHEMBL16065011 | 0.85 | CTSC (0.62) | CTSCCTSK | |
| SCHEMBL18828603 | 0.84 | CTSC (0.66) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970228-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2017-05-10 | — | — | EP | disclosed |