Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15797825 | 1.00 | HRH3 (0.52) | HRH3KCNH2SSTR4HDAC4KCNQ3 | |
| SCHEMBL15797826 | 1.00 | HRH3 (0.52) | HRH3KCNH2SSTR4HDAC4KCNQ3 | |
| SCHEMBL15805108 | 1.00 | HRH3 (0.52) | HRH3KCNH2SSTR4HDAC4KCNQ3 | |
| SCHEMBL15805085 | 1.00 | HRH3 (0.52) | HRH3KCNH2SSTR4HDAC4KCNQ3 | |
| SCHEMBL1473448 | 0.89 | HRH3 (0.40) | HRH3MAPTPKM | |
| SCHEMBL15314513 | 0.86 | HRH3 (0.55) | HRH3KCNH2SSTR4HDAC4SSTR1 | |
| SCHEMBL451266 | 0.86 | HRH3 (0.55) | HRH3KCNH2SSTR4HDAC4SSTR1 | |
| SCHEMBL455274 | 0.86 | HRH3 (0.55) | HRH3KCNH2SSTR4HDAC4SSTR1 | |
| SCHEMBL12128172 | 0.86 | HRH3 (0.55) | HRH3KCNH2SSTR4HDAC4SSTR1 | |
| SCHEMBL15797832 | 0.83 | KDM1A (0.44) | MAPTPKMKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931708-B1 | CYCLOPROPYLBORONIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF | DIVERCHIM (FR) | 2017-05-10 | — | — | EP | disclosed |