Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 5/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18828986 | 1.00 | CDK7 (0.49) | CDK7FLT3GSK3BGSK3AGPR84 | |
| SCHEMBL18812687 | 1.00 | CDK7 (0.49) | CDK7FLT3GSK3BGSK3AGPR84 | |
| SCHEMBL18812678 | 0.89 | CDK7 (0.48) | CDK7GSK3BGSK3AJAK2JAK1 | |
| SCHEMBL18828988 | 0.89 | CDK7 (0.48) | CDK7GSK3BGSK3AJAK2JAK1 | |
| SCHEMBL18828989 | 0.89 | CDK7 (0.48) | CDK7GSK3BGSK3AJAK2JAK1 | |
| SCHEMBL18932071 | 0.86 | CDK7 (0.49) | CDK7FLT3GSK3BGSK3AGPR84 | |
| SCHEMBL18828963 | 0.81 | FLT3 (0.60) | FLT3GSK3BKDM4ESTAT3HIF1A | |
| SCHEMBL18828964 | 0.81 | FLT3 (0.60) | FLT3GSK3BKDM4ESTAT3HIF1A | |
| SCHEMBL18812671 | 0.81 | FLT3 (0.60) | FLT3GSK3BKDM4ESTAT3HIF1A | |
| SCHEMBL18828978 | 0.80 | MAPK10 (0.52) | FLT3KMT2ACDK2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158642-A1 | COMPOSITION FOR INDUCING CELL REPROGRAMMING | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-06-08 | — | — | US | disclosed |
| EP-3165523-A2 | COMPOSITION FOR INDUCING CELL REPROGRAMMING | Gwangju Institute of Science and Technology (KR) | 2017-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158642-A1 | COMPOSITION FOR INDUCING CELL REPROGRAMMING | MCL1, IRF3, STING1 | CDK7 653/4885FLT3 357/4885GSK3B 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.