Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 6/20 | 0.48 |
| ▸ | JAK2 | O60674 | 3/20 | 0.47 |
| ▸ | JAK1 | P23458 | 3/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.47 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18812678 | 1.00 | CDK7 (0.48) | CDK7JAK2JAK1MAP2K4MAPK1 | |
| SCHEMBL18828988 | 1.00 | CDK7 (0.48) | CDK7JAK2JAK1MAP2K4MAPK1 | |
| SCHEMBL18828985 | 0.89 | CDK7 (0.49) | CDK7JAK2JAK1GSK3AGSK3B | |
| SCHEMBL18828986 | 0.89 | CDK7 (0.49) | CDK7JAK2JAK1GSK3AGSK3B | |
| SCHEMBL18812687 | 0.89 | CDK7 (0.49) | CDK7JAK2JAK1GSK3AGSK3B | |
| SCHEMBL18812677 | 0.85 | CDK7 (0.63) | CDK7JAK2JAK1MAPK1FGFR1 | |
| SCHEMBL18828978 | 0.83 | MAPK10 (0.52) | CDK2 | |
| SCHEMBL18829002 | 0.83 | MAPK10 (0.52) | CDK2 | |
| SCHEMBL18932050 | 0.83 | CDK7 (0.49) | CDK7JAK2JAK1MAP2K4MAPK1 | |
| SCHEMBL18812674 | 0.80 | JAK2 (0.57) | JAK2JAK1MAP2K4MAPK1MAPKAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165523-A2 | COMPOSITION FOR INDUCING CELL REPROGRAMMING | Gwangju Institute of Science and Technology (KR) | 2017-05-10 | — | — | EP | disclosed |