SCHEMBL18829072

SCHEMBL18829072

COCC(C)CN(C)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13202681 0.79
SCHEMBL24477348 0.78
SCHEMBL17828084 0.77 PIK3CD (0.34) PIK3CD
SCHEMBL21030402 0.76 PIK3CD (0.35) PIK3CD
SCHEMBL24224755 0.76 PIK3CD (0.35) PIK3CD
SCHEMBL18829504 0.75
SCHEMBL14459967 0.73 PIK3CD (0.41) PIK3CD
SCHEMBL21140988 0.72 PIK3CD (0.41) PIK3CD
SCHEMBL22992415 0.71 KCNA5 (0.33) PIK3CD
SCHEMBL18829080 0.71 PIK3CD (0.40) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284741-A1 ANTIVIRAL COMPOUNDS Gilead Pharmasset LLC (US) 2018-02-21 EP disclosed
EP-2640719-B1 ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC (US) 2017-05-10 EP disclosed