⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18829504 | 0.82 | — | — | |
| SCHEMBL24492321 | 0.80 | HTT (0.30) | — | |
| SCHEMBL18829072 | 0.78 | PIK3CD (0.38) | — | |
| SCHEMBL19542935 | 0.76 | — | — | |
| SCHEMBL24477253 | 0.74 | — | — | |
| SCHEMBL23350193 | 0.74 | — | — | |
| SCHEMBL13380873 | 0.73 | CA1 (0.35) | — | |
| SCHEMBL24641263 | 0.69 | — | — | |
| SCHEMBL23901745 | 0.67 | LMNA (0.33) | — | |
| SCHEMBL23901737 | 0.67 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169660-A1 | CYCLIC AMINO-PYRAZINECARBOXAMIDE COMPOUNDS AND USES THEREOF | SILVERBACK THERAPEUTICS INC (US) | 2022-06-02 | — | — | US | disclosed |