Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947206 | 0.80 | NPC1 (0.51) | HTTGRIN2BKMT2AMAPTNOS2 | |
| SCHEMBL5799220 | 0.80 | NPC1 (0.51) | HTTGRIN2BKMT2AMAPTNOS2 | |
| SCHEMBL5797993 | 0.74 | NPSR1 (0.53) | HTTCTSDNOS2GAANPC1 | |
| SCHEMBL8233732 | 0.72 | USP2 (0.41) | HTTGRIN2BMEN1KMT2AMAPT | |
| SCHEMBL24451313 | 0.72 | HPGD (0.56) | HTTMEN1KMT2ATSHRMAPT | |
| SCHEMBL25683635 | 0.71 | DHODH (0.54) | HTTMEN1KMT2ATSHRNPC1 | |
| SCHEMBL1448967 | 0.70 | HPGD (0.51) | HTTMEN1KMT2ATSHRMAPT | |
| SCHEMBL1448963 | 0.70 | HPGD (0.51) | HTTMEN1KMT2ATSHRMAPT | |
| SCHEMBL1448965 | 0.70 | HPGD (0.51) | HTTMEN1KMT2ATSHRMAPT | |
| SCHEMBL9133454 | 0.70 | NPC1 (0.50) | GRIN2BCTSDTSHRMAPTNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373758-B1 | PHOTOCHROMIC OPTICAL ARTICLES PREPARED WITH REVERSIBLE THERMOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2017-05-10 | — | — | EP | disclosed |