Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799220 | 1.00 | NPC1 (0.51) | NPC1RAB9AMAPTPKMCDK5 | |
| SCHEMBL164345 | 0.84 | GRIN2B (0.59) | NPC1MAPTTDP1HTTNOS2 | |
| SCHEMBL987917 | 0.84 | GRIN2B (0.59) | NPC1MAPTTDP1HTTNOS2 | |
| SCHEMBL2206812 | 0.84 | GRIN2B (0.59) | NPC1MAPTTDP1HTTNOS2 | |
| SCHEMBL9133458 | 0.82 | NPC1 (0.50) | NPC1RAB9AMAPTTDP1LTA4H | |
| SCHEMBL9133454 | 0.82 | NPC1 (0.50) | NPC1RAB9AMAPTTDP1LTA4H | |
| Hydrochloric Acid SCHEMBL4741316 | 0.81 | GRIN2B (0.67) | NPC1RAB9AMAPTCDK5CDK5R1 | |
| SCHEMBL18829673 | 0.80 | HTT (0.47) | NPC1RAB9AMAPTGAAHTT | |
| SCHEMBL27780177 | 0.79 | NOS2 (0.50) | MAPTHTTKMT2ANOS2L3MBTL1 | |
| SCHEMBL27780168 | 0.79 | GRIN2B (0.65) | NPC1RAB9AMAPTGAANOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015159170-A2 | IMPROVED PROCESS FOR THE SYNTHESIS OF 1-(4-METHOXYPHENYL) ETHYLAMINE AND ITS ISOMERS | SUVEN LIFE SCIENCES LIMITED (IN) | 2015-10-22 | — | — | WO | disclosed |
| US-20140228579-A1 | METHOD FOR THE CATALYTIC REDUCTION OF ACID CHLORIDES AND IMIDOYL CHLORIDES | Brock Unviersity (CA) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228579-A1 | METHOD FOR THE CATALYTIC REDUCTION OF ACID CHLORIDES AND IMIDOYL CHLORIDES | CA6, RUVBL2, HACL2 | NPC1 2618/4885RAB9A 854/4885MAPT 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.