Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | TPMT | P51580 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571301 | 0.84 | CA12 (0.53) | CA12CA1CA2CA4CA6 | |
| SCHEMBL18830678 | 0.84 | MAPT (0.52) | HDAC1HDAC8HDAC6TSHRRAB9A | |
| SCHEMBL11338267 | 0.82 | RAD52 (0.51) | MAPK1HDAC1HDAC8HDAC6TSHR | |
| SCHEMBL24714329 | 0.82 | MAPT (0.57) | MAPK1TSHRHTTLMNAGAA | |
| SCHEMBL10742633 | 0.80 | CA12 (0.64) | CA12CA1CA2CA4CA6 | |
| SCHEMBL29721118 | 0.79 | HDAC1 (0.54) | CA12CA1CA2CA4CA6 | |
| SCHEMBL30870991 | 0.79 | CA12 (0.54) | CA12CA1CA2CA4CA6 | |
| SCHEMBL21408921 | 0.79 | HDAC1 (0.54) | CA12CA1CA2CA4CA6 | |
| SCHEMBL27968626 | 0.79 | CA12 (0.48) | CA12CA1CA2CA4CA6 | |
| Hydrochloric Acid SCHEMBL6822458 | 0.78 | CA12 (0.61) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760838-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-05-10 | — | — | EP | disclosed |