Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086541 | 0.79 | CNR1 (0.47) | ESR1VDRALDH1A1KDM4EMEN1 | |
| SCHEMBL31294747 | 0.79 | HSD11B1 (0.41) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL31294831 | 0.78 | HPGD (0.38) | ALDH1A1 | |
| SCHEMBL11494029 | 0.77 | KMT2A (0.47) | ESR1ALDH1A1KMT2A | |
| SCHEMBL31294661 | 0.77 | SYK (0.40) | ALDH1A1CNR2 | |
| SCHEMBL1349277 | 0.76 | TSHR (0.49) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL31294663 | 0.76 | KMT2A (0.46) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL11506920 | 0.76 | HSD11B1 (0.40) | — | |
| SCHEMBL1349483 | 0.76 | NPSR1 (0.47) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL314187 | 0.75 | MEN1 (0.43) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |