Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050147 | 0.83 | KCNH2 (0.57) | KCNH2CA2CA4CA5ACA12 | |
| SCHEMBL4441980 | 0.83 | KCNH2 (0.62) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL3066816 | 0.79 | KCNH2 (0.53) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL108542 | 0.78 | KCNH2 (0.47) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL6827880 | 0.78 | KCNH2 (0.47) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL3732748 | 0.78 | KCNH2 (0.47) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL11782607 | 0.78 | KCNH2 (0.47) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL111556 | 0.78 | KCNH2 (0.47) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL11219090 | 0.78 | KCNH2 (0.47) | KCNH2HPGDSMN1; SMN2MAPTMGLL | |
| SCHEMBL2502560 | 0.78 | KCNH2 (0.47) | KCNH2HPGDSMN1; SMN2MAPTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619361-B1 | Phosphorothioate coking inhibitors | NALCO CHEMICAL CO (US) | 1998-08-05 | — | — | EP | claimed |
| EP-0619361-A2 | Phosphorothioate coking inhibitors | NALCO CHEMICAL COMPANY (US) | 1994-10-12 | — | — | EP | claimed |
| US-5354450-A | Phosphorothioate coking inhibitors | NALCO CHEMICAL COMPANY (US) | 1994-10-11 | — | — | US | claimed |
| JP-6184375-A | — | — | None | — | — | JP | disclosed |
| US-20110100015-A1 | GAS TURBINE SYSTEM TO INHIBIT COKE FORMATION AND METHODS OF USE | GENERAL ELECTRIC COMPANY (US) | 2011-05-05 | — | — | US | disclosed |
| US-6040091-A | HAVING FIRE RETARDANT PROPERTIES | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0619361-B1 | Phosphorothioate coking inhibitors | NALCO CHEMICAL CO (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0619361-A2 | Phosphorothioate coking inhibitors | NALCO CHEMICAL COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5354450-A | Phosphorothioate coking inhibitors | NALCO CHEMICAL COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| JP-H06184375-A | FLAME-RETARDANT POLYPROPYLENE RESIN COMPOSITION | TOSOH CORP | 1994-07-05 | — | — | JP | disclosed |
| US-4340705-A | PHOSPHORUS COMPONENT COORDINATION CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-07-20 | — | — | US | disclosed |