SCHEMBL108542

SCHEMBL108542

O=P(O)(O)Sc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.47
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MGLL Q99685 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SRC P12931 2/20 0.41
CFTR P13569 1/20 0.41
PTPN1 P18031 1/20 0.39
FFAR1 O14842 1/20 0.39
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4656192 0.97 KCNH2 (0.45) KCNH2CA2CA4CA5AMAPT
SCHEMBL6831542 0.86 ACP3 (0.48) CA2CA4CA5AMAPTSMN1; SMN2
SCHEMBL707305 0.84 KCNH2 (0.47) KCNH2CA2CA4CA5AMAPT
SCHEMBL5351835 0.80 KCNH2 (0.44) KCNH2CA2CA4CA5AMAPT
SCHEMBL2502560 0.79 KCNH2 (0.47) KCNH2CA2CA4CA5AMAPT
SCHEMBL6831537 0.78 CA2 (0.52) KCNH2CA2CA4CA5AMAPT
SCHEMBL1883203 0.78 KCNH2 (0.61) KCNH2CA2CA4CA5AMAPT
SCHEMBL10867968 0.77 NR1H2 (0.48) CA2CA4CA5AMAPTHPGD
SCHEMBL3056851 0.77 KCNH2 (0.46) KCNH2CA2CA4CA5AMAPT
SCHEMBL6832367 0.77 HPGD (0.46) KCNH2CA2CA4CA5AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946800-A Grease composition and method for producing same 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-117946786-A Grease composition and method for producing same 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-117917418-A Organic sulfur-phosphorus compound, preparation method and application thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-117917466-A Lubricating oil composition for hybrid automobile engine and preparation method thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-117917467-A Lubricating oil composition for electric automobile shock absorber and preparation method thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-117917465-A Worm gear oil composition and preparation method thereof 中国石油化工股份有限公司 2024-04-23 CN claimed
CN-111961252-B Fire retardant phenylphosphonyl methyl silicone cage-shaped ester amine compound and preparation method thereof 苏州科技大学 2022-04-26 CN claimed
CN-111961252-A Fire retardant phenylphosphonyl methyl silicone cage-shaped ester amine compound and preparation method thereof 苏州科技大学 2020-11-20 CN claimed
US-12595433-B2 Organic phosphorus compound, preparation method therefor, and uses thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2026-04-07 US disclosed
US-20250034476-A1 ORGANIC PHOSPHORUS COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-01-30 US disclosed
US-12122974-B2 Organophosphorus compound, and preparation process and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-10-22 US disclosed
CN-117946800-A Grease composition and method for producing same 中国石油化工股份有限公司 2024-04-30 CN disclosed
CN-117946786-A Grease composition and method for producing same 中国石油化工股份有限公司 2024-04-30 CN disclosed
CN-117917465-A Worm gear oil composition and preparation method thereof 中国石油化工股份有限公司 2024-04-23 CN disclosed
US-4617584-A GOOD HUMIDITY RESISTANCE, CORROSION RESITANCE; CURED NOVOLAC TYPE EPOXY RESIN, NOVOLAC PHENOLIC RESIN AND ORGANIC PHOSPHOROUS COMPOUND TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1986-10-14 US disclosed
EP-0176480-A1 Substituted S-(hydroxyphenyl) thiophosphates CIBA-GEIGY AG (CH) 1986-04-02 EP disclosed
EP-0128006-A2 A soil-disease-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP disclosed
EP-0120981-A1 Resin encapsulation type semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 1984-10-10 EP disclosed
US-4308197-A POLYIMIDE OR POLYEPOXIDE AND AN AMMONIUM OR AMINE SALT OF AN ORGANIC PHOSPHONIC OR PHOSPHINIC ACID; CHAR STABILITY; AIRCRAFT MCDONNELL DOUGLAS CORPORATION (US) 1981-12-29 US disclosed
US-4086213-A FOR POLYURETHANE SYNTHESIS AIR PRODUCTS AND CHEMICALS, INC. (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12122974-B2 Organophosphorus compound, and preparation process and use thereof PON1, GK, FEN1 KCNH2 4195/4885CA2 2378/4885CA4 2173/4885
US-12595433-B2 Organic phosphorus compound, preparation method therefor, and uses thereof NOTUM, GC, PHOSPHO1 KCNH2 4553/4885CA2 821/4885CA4 825/4885
US-20250034476-A1 ORGANIC PHOSPHORUS COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF SOST, NOTUM, WEE1 KCNH2 4512/4885CA2 1742/4885CA4 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.