Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350331 | 0.81 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25399154 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6583252 | 0.76 | CYP1A2 (0.45) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31558555 | 0.76 | CYP1A2 (0.45) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6284303 | 0.76 | PDGFRB (0.43) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30765972 | 0.76 | PDGFRB (0.43) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4706566 | 0.75 | MAPT (0.43) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2975400 | 0.74 | ATM (0.40) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5434215 | 0.73 | KMT2A (0.44) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11900588 | 0.73 | ITGB1 (0.39) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168224-A1 | ORGANOZINC COMPOSITION | Ludwig-Maximilians-Universität München (DE) | 2017-05-17 | — | — | EP | disclosed |
| EP-3168224-A1 | ORGANOZINC COMPOSITION | Ludwig-Maximilians-Universität München (DE) | 2017-05-17 | — | — | EP | disclosed |