Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2319900 | 1.00 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL668709 | 1.00 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL306103 | 1.00 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL21840 | 1.00 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM | |
| Ammonia Solution, Strong SCHEMBL21839 | 1.00 | MAPT (0.47) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL432548 | 0.99 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL13458992 | 0.99 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL63297 | 0.99 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL14599149 | 0.99 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM | |
| SCHEMBL7915441 | 0.99 | MAPT (0.48) | MAPTNPSR1ALDH1A1TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9778257-B2 | Autoantibody detection method, method for testing possibility of autoimmune disease contraction, autoantibody detection reagent, and autoimmune disease test reagent | OSAKA UNIVERSITY (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20170176432-A1 | AUTOANTIBODY DETECTION METHOD, METHOD FOR TESTING POSSIBILITY OF AUTOIMMUNE DISEASE CONTRACTION, AUTOANTIBODY DETECTION REAGENT, AND AUTOIMMUNE DISEASE TEST REAGENT | OSAKA UNIVERSITY (JP) | 2017-06-22 | — | — | US | disclosed |
| EP-2251425-B1 | Process for producing protein A-like protein with use of Brevibacillus genus bacterium | KANEKA CORP (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-7939077-B2 | DNA sequences that code antibodies or fragments; genetic vectors and host cells transformed by the vector, used for diagnosis and prophylaxis of cancer | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-05-10 | — | — | US | disclosed |
| EP-1676862-B1 | RECOMBINANT ANTIBODY AGAINST HUMAN INSULIN-LIKE GROWTH FACTOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2010-12-22 | — | — | EP | disclosed |
| EP-2251425-A1 | Process for producing protein A-like protein with use of Brevibacillus genus bacterium | Kaneka Corporation (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-7763246-B2 | Platelet-derived growth factor receptor specific immunoglobulin for diagnosis, prevention and treatment of cell proliferative disorders | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-1505075-B1 | ANTIBODY TO HUMAN INSULIN-LIKE GROWTH FACTOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-10-07 | — | — | EP | disclosed |
| US-7498415-B2 | Recombinant antibody against human insulin-like growth factor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-7438911-B2 | Antibody against human insulin-like growth factor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-10-21 | — | — | US | disclosed |
| US-7241568-B2 | Anti-fibroblast growth factor-8 monoclonal antibody | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-10 | — | — | US | disclosed |
| EP-1767640-A1 | PROCESS FOR PRODUCING PROTEIN A-LIKE PROTEIN WITH USE OF BREVIBACILLUS GENUS BACATERIUM | Kaneka Corporation (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20060240015-A1 | Recombinant antibody against human insulin-like growth factor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-10-26 | — | — | US | disclosed |
| US-20060165695-A1 | Antibody against human insulin-like growth factor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1676862-A1 | RECOMBINANT ANTIBODY AGAINST HUMAN INSULIN-LIKE GROWTH FACTOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-07-05 | — | — | EP | disclosed |
| EP-1505075-A1 | ANTIBODY TO HUMAN INSULIN-LIKE GROWTH FACTOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-20040253234-A1 | Humanized antibody against fibroblast growth factor-8 and antibody fragment thereof | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1422243-A1 | HUMANIZED ANTIBODY AGAINST FIBROBLAST GROWTH FACTOR−8 AND FRAGMENT OF THE ANTIBODY | Kyowa Hakko Kogyo Co., Ltd (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-20040091480-A1 | Anti-fibroblast growth factor-8 monoclonal antibody | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1308509-A1 | NOVEL PHYSIOLOGICALLY ACTIVE PEPTIDE AND USE THEREOF | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-05-07 | — | — | EP | disclosed |