Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL306103

CCn1c(=NN=c2sc3cc(S(=O)(=O)O)ccc3n2CC)sc2cc(S(=O)(=O)O)ccc21.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 8/20 0.42
ALDH1A1 P00352 7/20 0.42
TSHR P16473 3/20 0.42
PKM P14618 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
KDM4E B2RXH2 6/20 0.39
NPC1 O15118 1/20 0.39
RECQL P46063 1/20 0.39
RAB9A P51151 1/20 0.39
PPARG P37231 1/20 0.38
NCOA2 Q15596 1/20 0.38
NCOA1 Q15788 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
MAPK1 P28482 1/20 0.38
HPGD P15428 4/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
GAA P10253 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL2319900 1.00 MAPT (0.47) MAPTNPSR1ALDH1A1TSHRPKM
Ammonia Solution, Strong SCHEMBL668709 1.00 MAPT (0.47) MAPTNPSR1ALDH1A1TSHRPKM
Ammonia Solution, Strong SCHEMBL21840 1.00 MAPT (0.47) MAPTNPSR1ALDH1A1TSHRPKM
Ammonia Solution, Strong SCHEMBL21839 1.00 MAPT (0.47) MAPTNPSR1ALDH1A1TSHRPKM
Ammonia Solution, Strong SCHEMBL1883384 1.00 MAPT (0.47) MAPTNPSR1ALDH1A1TSHRPKM
SCHEMBL432548 0.99 MAPT (0.48) MAPTNPSR1ALDH1A1TSHRPKM
SCHEMBL13458992 0.99 MAPT (0.48) MAPTNPSR1ALDH1A1TSHRPKM
SCHEMBL63297 0.99 MAPT (0.48) MAPTNPSR1ALDH1A1TSHRPKM
SCHEMBL14599149 0.99 MAPT (0.48) MAPTNPSR1ALDH1A1TSHRPKM
SCHEMBL7915441 0.99 MAPT (0.48) MAPTNPSR1ALDH1A1TSHRPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60126100-A None JP disclosed
EP-2314686-B2 Cells producing antibody compositions KYOWA KIRIN CO LTD (JP) 2023-06-21 EP disclosed
EP-2278003-B2 Method for controlling the activity of immunologically functional molecule KYOWA KIRIN CO LTD (JP) 2020-08-05 EP disclosed
EP-2270147-B2 METHOD FOR CONTROLLING THE ACTIVITY OF IMMUNOLOGICALLY FUNCTIONAL MOLECULE KYOWA KIRIN CO LTD (JP) 2020-07-22 EP disclosed
US-10590203-B2 Human CDR-grafted antibody and antibody fragment thereof KYOWA KIRIN CO., LTD. (JP) 2020-03-17 US disclosed
EP-2270150-B2 METHOD FOR CONTROLLING THE ACTIVITY OF IMMUNOLOGICALLY FUNCTIONAL MOLECULE KYOWA HAKKO KIRIN CO LTD (JP) 2019-08-07 EP disclosed
US-10233475-B2 Antibody composition-producing cell KYOWA HAKKO KIRIN CO., LTD (JP) 2019-03-19 US disclosed
US-10233247-B2 Method of modulating the activity of functional immune molecules KYOWA HAKKO KIRIN CO., LTD (JP) 2019-03-19 US disclosed
US-10131711-B2 Human CDR-grafted antibody and antibody fragment thereof KYOWA HAKKO KIRIN CO., LTD. (JP) 2018-11-20 US disclosed
US-20180030146-A1 HUMAN CDR-GRAFTED ANTIBODY AND ANTIBODY FRAGMENT THEREOF KYOWA HAKKO KIRIN CO., LTD. (JP) 2018-02-01 US disclosed
US-20040253234-A1 Humanized antibody against fibroblast growth factor-8 and antibody fragment thereof KYOWA HAKKO KIRIN CO., LTD. (JP) 2004-12-16 US disclosed
EP-1449850-A1 HUMAN CDR-GRAFTED ANTIBODIES AND ANTIBODY FRAGMENTS THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-08-25 EP disclosed
EP-1422243-A1 HUMANIZED ANTIBODY AGAINST FIBROBLAST GROWTH FACTOR−8 AND FRAGMENT OF THE ANTIBODY Kyowa Hakko Kogyo Co., Ltd (JP) 2004-05-26 EP disclosed
US-20040091480-A1 Anti-fibroblast growth factor-8 monoclonal antibody KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-05-13 US disclosed
EP-1331266-A1 CELLS PRODUCING ANTIBODY COMPOSITIONS Kyowa Hakko Kogyo Co., Ltd (JP) 2003-07-30 EP disclosed
US-20030115614-A1 Complementarity region determination antibodies; culture product; antiinflammatory agents, autoimmune diseases, viricides, bactericides KYOWA KIRIN CO., LTD. (JP) 2003-06-19 US disclosed
EP-1308509-A1 NOVEL PHYSIOLOGICALLY ACTIVE PEPTIDE AND USE THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-05-07 EP disclosed
EP-1229125-A1 PROCESS FOR PRODUCING POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2002-08-07 EP disclosed
EP-1176195-A1 METHOD FOR CONTROLLING THE ACTIVITY OF IMMUNOLOGICALLY FUNCTIONAL MOLECULE KYOWA HAKKO KOGYO CO., LTD. (JP) 2002-01-30 EP disclosed
JP-S60126100-A DETERMINATION OF ACTIVITY OF ANGIOTESIN I CONVERTING ENZYME KURABO IND LTD 1985-07-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10233247-B2 Method of modulating the activity of functional immune molecules FCGR3B, FCGR1A, FCGR2A MAPT 4454/4885NPSR1 1530/4885ALDH1A1 4580/4885
US-10233475-B2 Antibody composition-producing cell FCGR3B, FCGR2A, FCGR1A MAPT 1617/4885NPSR1 4566/4885ALDH1A1 4618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.