Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 16/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505259 | 0.90 | P2RX3 (0.39) | P2RX3TRPC5TP53 | |
| SCHEMBL18835112 | 0.85 | P2RX3 (0.36) | P2RX3TRPC5TP53 | |
| SCHEMBL21499638 | 0.83 | TBXA2R (0.33) | P2RX3 | |
| SCHEMBL20432348 | 0.83 | P2RX3 (0.40) | P2RX3TRPC5TP53 | |
| SCHEMBL21316298 | 0.83 | P2RX3 (0.46) | P2RX3TRPC5TP53 | |
| SCHEMBL21499643 | 0.82 | P2RX3 (0.45) | P2RX3TRPC5 | |
| SCHEMBL21499690 | 0.82 | P2RX3 (0.39) | P2RX3TRPC5TP53 | |
| SCHEMBL18834374 | 0.82 | P2RX3 (0.38) | P2RX3TRPC5TP53 | |
| SCHEMBL21499648 | 0.81 | TRPC4 (0.40) | P2RX3TRPC5TP53 | |
| SCHEMBL21499689 | 0.80 | PDE5A (0.41) | P2RX3TRPC5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |