Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 7/20 | 0.51 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076060 | 0.94 | TRPC5 (0.52) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL16027905 | 0.90 | TRPC5 (0.54) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL31466659 | 0.90 | TRPC5 (0.54) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL16028882 | 0.88 | TRPC5 (0.54) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL31466662 | 0.88 | TRPC5 (0.54) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL16028313 | 0.87 | TRPC5 (0.52) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL30171340 | 0.87 | TRPC5 (0.53) | TRPC5TRPC4KCNH2TRPC1PCSK9 | |
| SCHEMBL16076080 | 0.87 | TRPC5 (0.53) | TRPC5TRPC4KCNH2TRPC1PCSK9 | |
| SCHEMBL31466621 | 0.86 | TRPC5 (0.67) | TRPC5TRPC4KCNH2TRPC1BRAF | |
| SCHEMBL16028318 | 0.86 | TRPC5 (0.67) | TRPC5TRPC4KCNH2TRPC1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |