Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222548 | 0.98 | HRH3 (0.39) | HRH3PSMB1PSMB5PSMB2NPC1 | |
| SCHEMBL22282270 | 0.80 | ALDH1A1 (0.37) | HRH3NPC1ALDH1A1KDM4E | |
| SCHEMBL5673600 | 0.79 | HRH3 (0.38) | HRH3PSMB1PSMB5PSMB2NPC1 | |
| SCHEMBL3387923 | 0.78 | ALDH1A1 (0.42) | HRH3NPC1TSHRALDH1A1KDM4E | |
| SCHEMBL14261168 | 0.78 | ALDH1A1 (0.42) | NPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL18062194 | 0.78 | KDM4E (0.33) | ALDH1A1KDM4EMAPT | |
| SCHEMBL28110383 | 0.77 | HRH3 (0.42) | HRH3PSMB1PSMB5PSMB2NPC1 | |
| SCHEMBL271825 | 0.77 | HRH3 (0.42) | HRH3PSMB1PSMB5PSMB2NPC1 | |
| SCHEMBL16527276 | 0.77 | HRH3 (0.42) | HRH3PSMB1PSMB5PSMB2NPC1 | |
| SCHEMBL11745202 | 0.77 | HRH3 (0.42) | HRH3PSMB1PSMB5PSMB2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751405-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| EP-0751407-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| EP-0751404-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| US-5391669-A | Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers | HYDRON LIMITED (GB) | 1995-02-21 | — | — | US | claimed |
| EP-0563299-A4 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | CESKOSLOVENSKA AKADEMIE VED (CS) | 1994-07-20 | — | — | EP | claimed |
| US-5270415-A | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | ALLERGAN INC. (US) | 1993-12-14 | — | — | US | claimed |
| EP-0563299-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | Hydron Limited (GB) | 1993-10-06 | — | — | EP | claimed |
| WO-1992011301-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | ALLERGAN, INC. (US) | 1992-07-09 | — | — | WO | claimed |
| EP-2397505-A1 | High water content silicone hydrogels | Bausch & Lomb Incorporated (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2222736-B1 | HIGH WATER CONTENT SILICONE HYDROGELS | BAUSCH & LOMB (US) | 2011-09-21 | — | — | EP | disclosed |
| US-7934830-B2 | High water content silicone hydrogels | BAUSCH & LOMB INCORPORATED (US) | 2011-05-03 | — | — | US | disclosed |
| EP-1394153-B1 | THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF | UNIMATEC CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7812157-B2 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| EP-2222736-A1 | HIGH WATER CONTENT SILICONE HYDROGELS | Bausch & Lomb Incorporated (US) | 2010-09-01 | — | — | EP | disclosed |
| EP-0563299-A4 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | CESKOSLOVENSKA AKADEMIE VED (CS) | 1994-07-20 | — | — | EP | disclosed |
| US-5270415-A | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | ALLERGAN INC. (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0563299-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | Hydron Limited (GB) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011301-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | ALLERGAN, INC. (US) | 1992-07-09 | — | — | WO | disclosed |
| US-4075237-A | Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof | GEIGY CHEMICAL CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-3949136-A | OIL REPELLENTS, WATERPROOFING TEXTILES | CIBA-GEIGY AG (CH) | 1976-04-06 | — | — | US | disclosed |