Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16029024 | 0.86 | ADORA2B (0.50) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL3114983 | 0.85 | ADORA1 (0.53) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL18834910 | 0.84 | PDE2A (0.53) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL16027743 | 0.83 | ADORA2A (0.49) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL3121598 | 0.83 | ADORA1 (0.53) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL3121149 | 0.81 | ADORA1 (0.52) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL29430494 | 0.81 | ADORA2B (0.49) | ADORA2AADORA2BALDH1A1LMNACYP1A2 | |
| SCHEMBL3120638 | 0.80 | ADORA2B (0.49) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL3112561 | 0.80 | ADORA2B (0.64) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL21499663 | 0.79 | ADORA2A (0.48) | ADORA2AADORA2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |