Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 15/20 | 0.68 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.68 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028300 | 0.94 | TRPC5 (0.78) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL19375488 | 0.93 | TRPC5 (0.67) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16028242 | 0.87 | TRPC5 (0.88) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16076248 | 0.87 | TRPC5 (0.67) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16076033 | 0.85 | TRPC5 (0.84) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16028303 | 0.85 | TRPC5 (0.73) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16364002 | 0.84 | TRPC5 (0.77) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL19505498 | 0.84 | TRPC5 (0.63) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16028261 | 0.84 | TRPC5 (0.69) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16028365 | 0.84 | TRPC5 (0.65) | TRPC5TRPC4TRPC1KCNH2PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |