Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 6/20 | 0.54 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.54 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834235 | 0.95 | TRPC5 (0.53) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL18834023 | 0.90 | TRPC5 (0.54) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL18834524 | 0.90 | TRPC5 (0.55) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL19374870 | 0.85 | NCOA3 (0.50) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL18835105 | 0.84 | TRPC5 (0.57) | TRPC5TRPC4TRPC1KCNH2MAOA | |
| SCHEMBL18834764 | 0.83 | TRPC5 (0.56) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16027825 | 0.81 | TRPC5 (0.60) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16029205 | 0.81 | TRPC4 (0.71) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16028477 | 0.79 | TRPC5 (0.72) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16028288 | 0.79 | TRPC5 (0.59) | TRPC5TRPC4TRPC1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |