SCHEMBL188358

SCHEMBL188358

CCCCCCCCCCCCCCCCCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 1.00
▸ MEN1 O00255 5/20 1.00
▸ KMT2A Q03164 5/20 1.00
▸ SLC25A20 O43772 3/20 1.00
▸ TP53 P04637 3/20 1.00
▸ TSHR P16473 3/20 1.00
▸ CYP2D6 P10635 2/20 1.00
▸ SLC6A5 Q9Y345 2/20 1.00
▸ CYP2C9 P11712 2/20 1.00
▸ HIF1A Q16665 2/20 1.00
▸ CYP2C19 P33261 2/20 1.00
▸ KDM4E B2RXH2 1/20 1.00
▸ CYP3A4 P08684 1/20 1.00
▸ NFKB1 P19838 1/20 1.00
▸ THPO P40225 1/20 1.00
▸ HSD17B10 Q99714 1/20 1.00
▸ MAPK1 P28482 5/20 0.76
▸ CYP1A2 P05177 4/20 0.76
▸ GMNN O75496 3/20 0.76
▸ LMNA P02545 3/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Palmitoyl-Carnitine SCHEMBL116634 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
SCHEMBL19182624 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
Palmitoyl-Carnitine SCHEMBL187668 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
SCHEMBL188359 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
Palmitoyl-Carnitine SCHEMBL855471 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
SCHEMBL8067110 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
SCHEMBL25373354 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
SCHEMBL1958560 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
SCHEMBL198686 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53
Palmitoyl-Carnitine SCHEMBL115183 1.00 MAPT (1.00) MAPTMEN1KMT2ASLC25A20TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 873 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122017090-A Biomarker combination for screening heart failure pleural effusion, application, system, equipment and medium 内蒙古医科大学附属医院(内蒙古自治区心血管研究所) 2026-05-12 — — CN claimed
US-20260125683-A1 TREATMENT OF CANCERS HAVING A DRUG-RESISTANT MESENCHYMAL CELL STATE DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-07 — — US claimed
CN-120089347-A Neonate genetic metabolism disease screening automatic interpretation system based on artificial intelligence 洛阳瀚纳生物科技有限公司 2025-06-03 — — CN claimed
CN-116087488-B Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof 中国医学科学院阜外医院 2025-06-03 — — CN claimed
US-12292445-B2 Methods of selecting subjects for treatment with metabolomic modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-06 — — US claimed
CN-119324053-A Model and index for evaluating aging delaying effect of estrogen replacement therapy and application of model and index 中国科学院北京基因组研究所(国家生物信息中心) 2025-01-17 — — CN claimed
CN-119224197-A Method for analyzing amino acid and/or acyl carnitine 株式会社岛津制作所 2024-12-31 — — CN claimed
CN-115840050-B Use of a reagent for detecting a metabolic marker in the preparation of a sleep disorder screening or diagnosis product 四川大学 2024-12-20 — — CN claimed
CN-118813788-A Biomarker for detecting or judging osteoporosis or osteoporosis disease risk and application thereof 上海中医药大学附属龙华医院 2024-10-22 — — CN claimed
CN-118818047-A Application of reagent for detecting biomarker combination in preparation of products for early warning or early auxiliary diagnosis of lung cancer transition of MetS-related lung cancer 上海市同仁医院 2024-10-22 — — CN claimed
US-20100116691-A1 BIOSENSOR FOR CONTINUOUS MONITORING OF METABOLITES AND PROTEINS AND METHODS OF MANUFACTURE THEREOF UNIVERSITY OF CONNECTICUT (US) 2010-05-13 — — US claimed
US-5385829-A Method of assaying for acyl-L-carnitines and short-chain acyl-carnitines ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1995-01-31 — — US claimed
EP-0215697-B1 ACYLCARNITINES AS ABSORPTION-ENHANCING AGENTS FOR DRUG DELIVERY THROUGH MUCOUS MEMBRANES OF THE NASAL, BUCCAL, SUBLINGUAL AND VAGINAL COMPARTMENTS MERCK & CO. INC. (US) 1992-03-25 — — EP claimed
US-4963525-A POLYPEPTIDES MERCK & CO., INC. (US) 1990-10-16 — — US claimed
EP-0162764-B1 COMPOSITION AND METHOD FOR ENHANCING ABSORPTION OF DRUGS FROM GASTROINTESTINAL TRACT USING ACYLCARNITINES MERCK & CO. INC. (US) 1989-08-09 — — EP claimed
US-4847298-A DOPA COMPOUNDS OR ANTIBIOTICS MERCK & CO., INC. (US) 1989-07-11 — — US claimed
US-4731360-A Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments MERCK & CO., INC. (US) 1988-03-15 — — US claimed
EP-0215697-A2 Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments MERCK & CO. INC. (US) 1987-03-25 — — EP claimed
EP-0162764-A1 Composition and method for enhancing absorption of drugs from gastrointestinal tract using acylcarnitines MERCK & CO. INC. (US) 1985-11-27 — — EP claimed
US-4537772-A Enhancing absorption of drugs from gastrointestinal tract using acylcarnitines MERCK & CO., INC. (US) 1985-08-27 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125683-A1 TREATMENT OF CANCERS HAVING A DRUG-RESISTANT MESENCHYMAL CELL STATE ACTR2, RPS6KB2, EPB41L2 MAPT 4006/4885MEN1 2877/4885KMT2A 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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